Prognostic value of lactate levels and lactate clearance in sepsis and septic shock with initial hyperlactatemia
نویسندگان
چکیده
منابع مشابه
Is lactate clearance impaired in septic shock?
In a recent article in Critical Care, Tapia and colleagues evaluated the relationship between exogenous lactate clearance and liver perfusion in a short-term model of endotoxemic shock [1]. The authors concluded that the very low portal-hepatic vein lactate gradient was indicative of the inability of the liver to metabolize the increased lactate load. Although we believe that the authors addres...
متن کاملEarly lactate clearance is associated with improved outcome in severe sepsis and septic shock.
OBJECTIVE Serial lactate concentrations can be used to examine disease severity in the intensive care unit. This study examines the clinical utility of the lactate clearance before intensive care unit admission (during the most proximal period of disease presentation) as an indicator of outcome in severe sepsis and septic shock. We hypothesize that a high lactate clearance in 6 hrs is associate...
متن کاملPentraxin-3, procalcitonin and lactate as prognostic markers in patients with sepsis and septic shock
The purpose of this study was to confirm the prognostic value of pentraxin-3 (PTX3), procalcitonin (PCT) and lactate in patients with severe infections requiring ICU management and to develop and validate a model to enhance mortality prediction by combining severity scores with biomarkers. We included 141 patients with the diagnosis of sepsis/septic shock. The levels of PTX3, PCT and lactate we...
متن کاملPrevalence and characteristics of non-lactate and lactate expressors in septic shock
PURPOSE The study's objective was to determine the proportion and patient characteristics of patients in vasopressor-dependent septic shock who presented without lactatemia. METHODS A retrospective review of patients presenting to an urban tertiary-care emergency department between December 2007 and September 2008 was conducted. Patients with a final diagnosis of septic shock requiring vasopr...
متن کاملSerial absolute lactate value < 4 versus relative 10% reduction as a predictor of mortality in severe sepsis and septic shock
Introduction Serial lactate measurements provide a valuable tool to risk-stratify patients, determine the presence of ongoing tissue hypoperfusion, and potentially evaluate efficacy of therapeutic interventions. Prior studies have shown lactate clearance to be a valuable predictor of patient outcomes, however some have defined adequate change in lactate by a decrease from baseline by 10% wherea...
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ژورنال
عنوان ژورنال: Medicine
سال: 2021
ISSN: 0025-7974,1536-5964
DOI: 10.1097/md.0000000000024835